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GSH and neurodegeneration The brain is particularly vulnerable to oxidative stress due to relatively lower antioxidant enzyme activities (SOD, GPx, GR and catalase) compared to other tissues

We followed patients from time of consult (ALivE) or admission (control) to 05/01/24, examining for the development of any liver decompensating event (ascites, variceal bleeding, hepatic encephalopathy, hepatorenal syndrome, hepatocellular cancer, or death) as our primary outcome

Bengel D., Oberschwabenklinik Ravensburg, Department of Neurology

Recently, our group found that substitution of Ser for Cys would not cause dramatic loss of GPx activity compared to changing those Cys to Sec 15,16