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287 Additionally, in a NASH mouse model, combined AFO-202 and N-163 treatment significantly increased gut microbial diversity, maximized Bacteroidetes abundance, and reduced Firmicutes abundance, exhibiting anticancer activity, suggesting the potential of combined intervention

Together, these antioxidants optimize individual benefits, significantly boosting overall health

The immunostained sections were scanned on a NanoZoomer NDP system (Hamamatsu Photonics, Shizuoka, Japan) with 20 resolution, or on a FV3000 confocal microscope (Olympus, Tokyo, Japan) with 4, 10 or 20 resolution

While nausea and vomiting were significantly more common in the amifostine group, sensory neuropathy was significantly less common (Hilpert 2005)

A randomized chemoprevention trial in Finland involving of 29,133 male smokers aged 5069 years found that beta-carotene supplementation increased the risk of lung cancer compared to placebo, highlighting how antioxidant effects can be influenced by confounding lifestyle factors such as tobacco and alcohol use (Middha et al., 2019)