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As expected, hepatic specific JAK2 -/- mice showed no hepatic IGF-1 synthesis and markedly reduced IGF-1 serum concentrations compared to wild-type mice

Pflugers Arch Eur J Physiol

On the other hand, no significant differences were found in the Glu or GABA levels, or in the Glu/GABA ratio between the ASD and control groups, which is in line with a recent meta-analysis of MRS studies in adults with ASD [25]

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: A systematic analysis for the global burden of disease study 2015