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This complication was frequently associated with nonketotic hyperglycemia in type 2 diabetes mellitus

In a scopolamine-induced cognitive impairment model in rats, Dihexa administered intracerebroventricularly (0.1 to 1.0 nmol), intraperitoneally (up to 0.5 mg/kg/day), or orally (up to 2.0 mg/kg/day) significantly improved performance on the Morris water maze (reduced latency to locate the hidden platform and increased time spent in the target quadrant during probe trials) compared with scopolamine-treated, Dihexa-untreated animals, with the highest doses producing performance indistinguishable from non-impaired controls

[Abstract]2024 May:223:116194

Visible changes in fat loss and muscle tone usually appear within 6 to 8 weeks

Statistical significance analyses were performed on data obtained from at least 3 experiments and 3 technical replicates