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Wiersma, M

Suggested Use: As a dietary supplement, take 1 softgel daily, preferably with a meal.Not manufactured with wheat, gluten, milk, egg, fish, shellfish or tree nut ingredients

Owing to its continuous nature, CKRT is not associated with major fluid or osmotic shifts and therefore has a reduced likelihood of aggravating the raised intracranial pressure associated with hyperammonaemia 40

10.1021/acs.jmedchem.0c01398 190 StalneckerC

It is diagnosed according to the Canadian consensus criteria, at least 6 months after onset when the following symptoms are present: fatigue, post-exertional malaise with a recovery period of at least 24 h, sleep dysfunction, pain, at least two neurological/neurocognitive symptoms and at least two symptoms involving the autonomic, neuroendocrine or immune system [19]