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Confirming the important role of the TGF/SMAD pathway in pancreatic fibrosis, we found that high glucose promoted the activation of PSCs in vitro

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Underlying mechanisms of hepatic microcirculatory modulation included improvement in HSCs and LSECs phenotype (ATXi: desmin -24%, Vcam1 -28%

Sikora E, Bielak-Zmijewska A, Dudkowska M, Krzystyniak A, Mosieniak G, Wesierska M, et al

The Trx system is commonly recognized as comprising of thioredoxin (TXN, Trx), thioredoxin reductase (TXNRD, TrxR), and nicotinamide adenine dinucleotide phosphate (NADPH)