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Description

Method for the inference of regulatory allosteric regulations after glucose administration To infer allosteric regulations, we used a method similar to our previous study 25

Protoplasts were collected at the interphase and transferred to a filter-sterilized W5 solution (2 mM MES pH 5.8, 154 mM NaCl, 125 mM CaCl 2 .2H 2 O, 5 mM KCl, 5 mM glucose) prior to counting in a Rosenthal chamber

Statin controls were defined as having ALT 1,000 in both MSC-EVs of healthy individuals and that of patients with DLC in our clinical trial

Class II GRX isoforms are involved in the coordination and transfer of Fe-S cluster on target proteins [64, 65] and become only redox-active after loss of the coordinated Fe-S cluster