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Nonpoint sources of freshwater pollution are agricultural activities (irrigation and drainage, pesticide and fertilizer applications, livestock waste), aquaculture activities, urban and industrial runoff, erosion associated with construction, mining and forest harvesting activities, atmospheric deposition, and hydrological modification (dams, diversions, channelization, over pumping of groundwater, siltation) (Loague and Corwin, 2006

10.1371/annotation/b84e1af7-c127-45c3-be22-76abd977600f PLoS One 26 CrossleyP.SutarY.TsoyI.MukkirwarS.aniewskiP.Herbst-KralovetzM

131 A general rule of thumb that is usually performed is to thoroughly perform a transcriptomic analysis in order to detect differential gene expression at the wound site, followed by gene ontology correlation studies in order to map the main metabolic pathways of genes related wound healing