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Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist cotadutide via modulating mitochondrial function and lipogenesis

Sakuraba et al., 2014

Regarding acute toxicity, according to the 2023 National Poison Data System annual report, there were 7905 reported unintentional heavy metal exposures in the United States, resulting in 26 serious health outcomes and two deaths

In this study, the authors showed that superoxide induced by DOCA-salt treatment caused increased vascular hydrogen peroxide production, which was significantly reduced by the eNOS inhibitor N G -nitro-L-arginine methyl ester