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Harmaline, a -carboline alkaloid that is found in the plant Peganum harmala , can inhibit the transcription factor Twist1 and restore FAO by upregulating the expression of PGC-1, PPAR and their downstream metabolic enzyme CPT1A, thereby alleviating RF [53]

10.1186/s12974-016-0490-1 118

Early brain response to low-dose radiation exposure involves molecular networks and pathways associated with cognitive functions, advanced aging and Alzheimers disease