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Furthermore, anti-TNF--treated inflammatory bowel disease (IBD) patients display a reduced PD risk compared with the untreated IBD patients, providing indirect evidence that long-term TNF- suppression may mitigate PD development [190]

Additional Information How to cite this article : Schamberger, A

doi: 10.3389/fphar.2025.1635624 Received 26 May 2025 Accepted 14 July 2025 Published 22 August 2025 Volume 16 - 2025 Edited by Marco Allinovi, Careggi University Hospital, Italy Reviewed by Manuel Lopez-Cabrera, Spanish National Research Council (CSIC), Spain Luciano D'Apolito, BioGeM Institute, Italy Updates Copyright 2025 Prasad, Chaturvedi, Singh, Udumula, Rawat, Jeyakumar, Jaiswal, Kumar and Agarwal