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Compared to exogenous recombinant GH (somatropin), Tesamorelin preserves the physiological pulsatility of endogenous secretion, maintaining better tissue response, avoiding GH-R desensitization, and presenting a more balanced metabolic profile (glycemic neutrality vs diabetogenic effect often documented with high-dose exogenous GH)

Comparing GH Secretagogues to GLP-1 Agonists Both GH secretagogues and GLP-1 agonists influence body composition, but through fundamentally different mechanisms

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I often use it in patients over 40 who are starting to feel the effects of age-related decline, says Dr

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