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Metabolic and lab monitoring: Check fasting glucose, HbA1c, lipid profile, liver enzymes, and thyroid at baseline, at three months, and then every six to twelve months

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In a multicenter, randomized, controlled trial in patients with venous leg ulcers, among those with ulcers of less than 12 months duration, significantly more of those treated with Dermagraft plus compression therapy were healed by week 12 than control participants treated with compression therapy alone (Harding 2013)

Nov-Dec 2022;7(6):e1045.doi:10.1097/PR9.0000000000001045

Many other kinds of vitamin B 12 deficiency have since been found