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In hyperoxia-induced models, RIPK3 not only boosts bioenergetics and mtROS production via upregulation of glycogen phosphorylase and pyruvate dehydrogenase complex E1 subunit, but also elevates mitochondrial NADPH oxidase 4 levels through post-transcriptional mechanisms, directly inducing mitochondrial damage (Uni and Choi, 2022)

Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with p53 and p21

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Conversely, G12V cells exhibit a much higher production and export of glutamine, greater synthesis of aspartate and a striking increase in ophthalmic acid synthesis (Fig

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