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M.WeiX.KikukawaY.TzameliI.PrasadD.et al (2015)

Alternative Terminology Crohns disease is documented under a variety of clinical, historical, and lay terms

Dosing information Usual Adult Dose for Pernicious Anemia: Initial dose: 100 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 days If clinical improvement and reticulocyte response is seen from the above dosing: 100 mcg every other day for 7 doses, then: 100 mcg every 3 to 4 days for 2 to 3 weeks, then: Maintenance dose: 100 to 1000 mcg monthly Duration of therapy: Life Comments: Administer concomitant folic acid if needed

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The approval and milestone chain runs from the first GLP-1 agonists for diabetes to today's multi-receptor agents: 2005 exenatide (Byetta), the first GLP-1 receptor agonist approved, for type 2 diabetes