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The 12-week Phase IIb trial in 300 obese adults, with 1mg daily dosing, produced an average weight loss of 2.6 kg compared with 0.8 kg in the placebo group

Genes Dev 29:26032616

Moreover, during the purification stage, high-speed centrifuges are also used to fractionate and separate components depending on size and density

Similarly, cyclic hydrostatic pressure enhances the chondrogenic differentiation of BMSCs (Ogawa et al., 2009) in a dose- and time-dependent manner, and shows synergistic effects when co-cultured with nucleus pulposus cells ( In contrast, static loading generally produces negative effects