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Results Bioinformatics reveal a Wnt-IGF1 link in articular cartilage To identify key downstream molecular players that drive the deleterious effects of excessive Wnt signaling activation in osteoarthritis, we took advantage of our genome-wide transcriptome dataset from human articular chondrocytes (hACs) wherein we inhibited the activity of the Disruptor of telomeric silencing-1 like (DOT1L) enzyme (geonr: GSE77916) 7

Study 7: Periodontal regeneration What they did: Clinical and preclinical experiments with GHK-Cu in regeneration of periodontal tissue (the ligament of the tooth, alveolar bone)

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LC-MS analysis A 2 L aliquot of each pretreated sample was injected into a BEH C18 column (100 mm 2.1 mm, 1.7 m

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