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PLoS ONE 12 (5), e0177970 (2017)

Commonly, initial treatment may involve weekly injections for a few weeks, followed by monthly maintenance doses as needed

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Next, diplotype frequencies per super-population were established

The mechanism that lowers postprandial glucose also means the stomach retains contents longer, which is relevant to anyone with pre-existing gastroparesis or significant GI motility disorders, and is a theoretical consideration around procedures requiring an empty stomach