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We and others recently showed that vitamin C, which has the capacity of reducing catalytic inactive Fe(III) to catalytic active Fe(II), upregulates the generation of 5hmC by acting as a cofactor for TET to hydroxylate 5mC 11,12,13,14,15

Mol Neurobiol 61 , 87028738 (2024)

Crit Rev Clin Lab Sci

A clinical study found that significant gene-environment interaction effects between CD38 A-carrier genotypes and chronic interpersonal stress, predicting greater social anxiety and depression symptoms [53]

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