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He also participated in the process of revising and editing the manuscript and approved the submitted version of the manuscript: Lonardo A Involved in data acquisition, analysis, and interpretation, revision of the manuscript for intellectual content, approval the submitted version of the manuscript: Ndrepepa G Availability of data and materials Not applicable

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Its function occurs via selenoproteins, which play critical roles in maintaining cellular redox homeostasis, regulating mitochondrial function, and modulating inflammatory signaling pathways

Drmic et al., 2017), neurotoxin cuprizone-induced multiple sclerosis in a rat model (Klicek et al., 2013), and magnesium overdose (Medvidovic-Grubisic et al., 2017))

Because of this potential effect on clot stabilization, individuals taking blood thinners may wish to avoid excessive use of sodium bicarbonate in baths, supplements, or antacids