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Activity & rest: Regular aerobic and resistance exercise is one of the strongest stimuli for mitochondrial biogenesis

These findings are drawn from preclinical research only

For example, as we described above that MTHFR polymorphism is associated with early onset of schizophrenia and the severity of depressive symptoms in MDD

Methylcobalamin B12 is also indicated in those with pernicious anemia, diabetes, neuropathy, heart disease, circadian rhythm sleep disorders, memory loss, depression, fatigue, AIDS, inflammatory bowel disease (IBD), Lyme disease, osteoporosis, tendonitis, psychiatric disorders, Alzheimers disease, liver and kidney disease, and asthma

So, the correlation of vitamin K with degree of improvement is puzzling