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In this analysis, eGFR, gender, and blood pressure were also related to the ACR, as reported 24 , suggesting the validity of our cohort

Additional investigations verifying the persistence of expression of previously identified markers of NP cells throughout development and ageing and large-scale comparative studies between animal and human notochordal/NP cell omics datasets will lead to the establishment of a consensus list of mature NP cell markers in the future

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Continuous education for personnel on changes in regulation and best practice