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Amifostine is FDA approved for the reduction of cumulative kidney toxicity from repeated cisplatin administration in patients with advanced ovarian cancer and non-small cell lung cancer (Ethyol 1999)

Another 3rd party stability study demonstrated that after 6 months at 104 degrees Fahrenheit (40 degrees Celsius) & 75% humidity, Tri-Fortify still exceeded label claim

They may cause volume depletion (reduced blood volume) and their effectiveness declines as renal function declines

Pediatric Res 52:301306 Shen J, Novotny EJ, Rothman DL (1998) In vivo lactate and -hydroxybutyrate editing using a pure-phase refocusing pulse train