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doi: 10.3389/fpsyt.2018.00559 62 SacchiSNovellisVPaoloneGNuzzoTIannottaMBelardoCet al

Linear mixed effects models were also used to determine associations between the changes in metabolites and changes in HRSD 17 over time, with age and gender as covariates, and using subjects as random variable

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doi: 10.1038/s41598-017-18371-1 29