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In the context of AD and other neurodegenerative disorders, silk nanoparticles enable versatile therapeutic delivery, including drugs and other active agents targeting specific cell types (Mathur and Gupta, 2010) and have demonstrated the ability to bypass the BBB and reach deep brain regions (Yonesi et al., 2021)

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This was because the drug did not significantly reduce weight in 536 subjects over the course of 24 weeks 2

ROS generation can also trigger autocatalytic reactions resulting in more free radicals that propagate the damage chain

A side-by-side illustration of cannula versus needle use in the infraorbital region: The cannula technique is shown creating a wide, even filler distribution with minimal trauma, making it ideal for patients with delicate skin or high vascular risk