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No direct human trial has evaluated any FOXO4-DRI dose

Systematic review and meta-analysis of remineralizing agents: outcomes on white spot lesions

Protein Sci 32:e4609

The mean dose was 384 mg/day

These findings underscore the intricate relationship between microglia and neurons, highlighting the critical role of microglial metabolism in maintaining optimal brain function and offering promising therapeutic potential for neurodegenerative diseases like AD