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- .In some embodiments, the method suitably comprises identifying at least one native amino acid residue in the peptide for substitution

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The direct interaction between MAPKAPK2 and Nrf2 remains to be confirmed through luciferase reporter or co-immunoprecipitation assays, and the association between MAPKAPK2 expression and promoter methylation should be validated using bisulfite sequencing or methylation array analyses

While current research does not show a notable reduction in B12 absorption, the changes in digestion could affect the absorption of nutrients, making it important to take supplements, including vitamin B12