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demonstrated that supplementation with probiotics as an adjunctive therapy significantly improved eradication rates (RR 1.10, 95% CI 1.061.14) and reduced the overall risk of side effects (RR 0.54, 95% CI 0.420.70) compared to standard therapy

Front Biosci 13:24002407 Sozzani S et al (2015) Chemokines as effector and target molecules in vascular biology

It documents a systemic failure to recognize contamination as a process signal , rather than a unit-level defect

These mechanistic distinctions become especially important when considering real-world chemical mixtures, because humans are rarely exposed to a single compound in isolation