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Trends Mol Med 9(8):360365 Surmeier DJ (2018) Determinants of dopaminergic neuron loss in Parkinsons disease

Glutathione Metabolism and its Implications for Health

The study found that daily supplementation with at least 400 IU of synthetic vitamin E (equivalent to 180 mg of RRR --tocopherol) resulted in a 4% increase in risk of death from any cause compared to placebo (125)