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Future studies should address this issue by clearly diagnosing either PD or manganism based on the known distinctions between the two diseases

Several regulatory mechanisms in the ferroptosis process protect cells from ferroptosis inhibition

This pattern aligns with findings from other supplement-exercise combinations across diverse nutritional agents, including saffron with circuit resistance training [32], spinach-derived thylakoids with high-intensity training [33], and spirulina with high-intensity interval training [34], suggesting that nutritional support can potentiate exercise-induced benefits across different supplement classes, exercise modalities, and health domains

Pediatrics 113 (5), e472e486

This study also suggests that the extract may alter the erythrocyte membrane in a way that renders red blood cells hostile and incompatible as parasite host cells or that it may prevent the parasite from entering the erythrocyte even when extract is not present in the growing media