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Section 419.66(d) includes three cost significance criteria that must each be met

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Based on a review retrieved from PubMed, it is one of the major chemical forms of B12 obtained from the diet, alongside methylcobalamin and adenosylcobalamin, and it sits at the centre of how cells take up and route the vitamin (Hannibal & Jacobsen, 2022, DOI)

They are not mutually exclusive a researcher can run 5-on/2-off within an 812 week block and still take the 4-week macro-break afterward

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