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Simultaneously, the elevated synovial fluid LPA levels enhanced FLS migration via the GPCR-PI3K/Akt axis, while the LPA antagonist Ki16425 inhibited synovial proliferation in an animal model (44)

Am J Psychiat 148: 14741486

Similarly, Rejuran S can also be performed this way

While BSO inhibition of GCL decreased glutathione and increased glutamate, sulforaphane induced GCL, and decreased glutamate while increasing glutathione (Fig