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Purification of a new neurotrophic factor from mammalian brain

Cost is a key obstacle: although the fundamental synthesis of RNA may be more economical than protein biologics, the requirement for sophisticated delivery methods, high-purity reagents, and stringent testing considerably increases the total expenditure

None of the 19 peptides on the Category 2 list have undergone full FDA drug approval for their commonly promoted therapeutic uses

The fragment pools produced (libraries) were diluted to the concentration of 4 nM, denatured, and diluted to 5 pM

As previously reported, iron chelators can attenuate symptoms and slow down the progression of AD, which shows the potential for novel therapeutic approaches (Nuez and Chana-Cuevas, 2018)