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Further, its remarkable therapeutic efficacy, coupled with minimal side effects, serves as a catalyst for advancing innovative treatments for HCC

observed that in the Frda/MCK mouse model, the initial phenotype after frataxin repression was the downregulation of Fe-S-dependent enzymes, which was then followed by iron accumulation [62]

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As our understanding of FRDA improves, our ability may improve to identify novel and promising pharmacological targets

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