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Discussion Based on our integrated genetic, protein structural, cell biological and organismic phenotypic analyses, we propose a model for the role of LPD-3 in C

The underlying mechanism primarily inhibits macrophagic Mincle-mediated necroptosis and inflammation affecting tubular epithelial cells

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Funding This work was supported by the National Science and Technology Major Project (2022ZD0117700), the National Natural Science Foundation of China (32270759) and the Research Foundation for Postdoctoral (AUGA5710026124)