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In fact, we have reported that uninephrectomy plus silencing of D 2 R in the remnant kidney increases blood pressure to the same extent as that observed with global deletion of the gene

The initial design of CAR-T cells targeting HIV was based on CD4, which increased the likelihood of new viral particles infecting engineered cells

Notably, several groups have reported aberrations in the constitutive trafficking, expression, and activity levels of glutamate transporters due to alterations in post-translational modifications in many disease states, which will be further discussed in Section 3

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Elevated levels of ROS and oxidative damage markers, such as 8-OHdG and MDA, have been detected in the synovial fluid and tissues of RA patients