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Building on this historical and technological context, the present section shifts focus from how these systems are developed to why they matter in practice, by dissecting the core functional roles that underpin their value in nutraceutical applications

Loo et al

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The use of CEUS in abdominal sarcoidosis has been evaluated in small case series or case reports [45], due to the scarcity of the cases and also to the fact that patients with hepatosplenic sarcoidosis rarely present with focal lesions, making them difficult candidates for CEUS (Figure 3)

These medications illustrate the core tension running through longevity medicine: they are prescription drugs with FDA approval for specific, well-established conditions, but their use in healthy-aging contexts represents off-label prescribing grounded in research interest rather than proven longevity outcomes in humans