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doi: 10.1002/1529-0131(200011)43:11 3.0.Co;2-k 132 SchettGZwerinaJFiresteinG

In this study, we used cryogenic electron microscopy (cryo-EM) to determine structures of Cagri bound to Gs-coupled, active, AMY 1 R, AMY 2 R, AMY 3 R and CTR and compared the mode of interaction of Cagri and the associated dynamics of the Cagri-bound receptor complexes with previously reported cryo-EM structures and dynamics of receptors bound to rat amylin (rAmy, all receptor subtypes), sCT (CTR, AMY 1 R, AMY 2 R) 15 or recently developed amylin-based peptides (CTR and/or AMY 3 R) 16

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Reclast solution for infusion must not be allowed to come in contact with any calcium or other divalent cation-containing solutions, and should be administered as a single intravenous solution through a separate vented infusion line

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