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Sahadevan R, Singh S, Binoy A, Sadhukhan S

doi: 10.3390/biomedicines10020289 187 MarteauPSeksikPJianR

10.1111/febs.15225 FEBS J

How do antioxidants support electron flow

There are 2 primary mechanisms: Ascorbic Acid (Ascorbate) uptake using sodium-dependent vitamin C transporter (SVCT) 1 or 2 Ascorbic Acid (Ascorbate) Recycling Ascorbic Acid (Ascorbate) transport using sodium-dependent vitamin C transporter (SVCT) 1 or 2 As shown below, SVCT 1 and SVCT 2 transport ascorbic acid or ascorbate into the cell against the concentration gradient (represented by the orange wedge in the figure below)