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KHYG1 and g - NK cells are CD38low/- NK cells which prove to be effective to kill MM cells by ADCC

Hyaluronic acid is a key metabolite of the ECM and plays an important role in moisturization, inflammation, cell migration and promotion of collagen synthesis ( Inflammation is known to upregulate hyaluronidase expression in various tissues, and plant bioactive metabolites can indirectly affect hyaluronidase activity by reducing pro-inflammatory cytokine production (Yi et al., 2019), ALE (83), Poria cocos bioactive metabolites (Subedi et al., 2017), Green mandarins (Wang et al., 2020) inhibit proinflammatory cytokines such as tumour necrosis factor alpha (TNF-), interleukin, and hyaluronidase

Importantly, our MAOB knockout experiments included both male and female mice, and no significant sex differences were observed in these analyses

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Research Monograph Series 88: Mechanisms of Cocaine Abuse and Toxicity p.125 (1988) DHHS Pub No