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Drug-induced liver injury (DILI) is a leading cause of acute liver failure and can be life-threatening

Until further research is available, health care professionals should be aware of the potential for drug-vitamin D interactions, assess their clients use of dietary supplements, and monitor serum 25(OH)D concentrations where indicated with the ultimate goal of achieving adequate serum 25(OH)D concentrations while optimizing drug efficacy and minimizing drug toxicity

[DOI] [PMC free article] [PubMed] 197.Ding J, et al

However, as with any supplement, it is crucial to consult with a healthcare professional before starting any new regimen, particularly if you have pre-existing health conditions or are taking other medications

Most of the clinical trials were also performed on unstratified trial participants, and for the most part trials did not obtain pre-treatment tumor biopsies that could have been useful in biomarker development