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Conclusion To answer the original question directly: high B12 levels themselves don't typically cause symptoms

The most serious complications described did not stem from glutathione itself, but from contaminated raw material used to prepare the infusion (PMID 29673413)

doi: 10.1002/ar.23781

Kostine M, Rouxel L, and Barnetche T, et al (2018) Rheumatic disorders associated with immune checkpoint inhibitors in patients with cancer-clinical aspects and relationship with tumour response: a single-centre prospective cohort study Ann Rheum Dis 77 (3) 393398 59