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Consistent with the toxicity of isoniazid in slow acetylators, there is an increased incidence of other drug toxicities in subjects carrying defective alleles, such as lupus erythematosus in patients treated with hydralazine or procainamide (Sim et al., 1988), and haemolytic anemia and inflammatory bowel disease after treatment with sulfasalazine (Chen et al., 2007)

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Alcohol, sugar and caffeine are all stimulants that the liver can use to produce more cholesterol, increasing levels of inflammation

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doi: 10.1038/onc.2016.499 141 MartinoJJWallBAMastrantoniEWilimczykBJLa CavaSNDegenhardtKet al