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[3] Hyperpigmentation in B12 deficiency occurs as a result of (1) decreased levels of reduced glutathione which activates tyrosinase and results in increased melanin synthesis, (2) defect in transfer of melanin from melanocytes to keratinocytes resulting in pigment incontinence, (3) increased biopterin in B12 deficiency increases hydroxylated phenylalanine which results in hyperpigmentation

You may also experience disturbed vision, pins and needles, muscle weakness, and changes in movement

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An intramuscular injection (IM injection) is a medical technique used to deliver medication directly into muscle tissue, where it can be absorbed quickly into the bloodstream

What are some other symptoms of B12 deficiency related to hair and skin