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Acknowledgements We are grateful for the support from the Laboratory Animal Center at National Taiwan University, College of Medicine and Flow Cytometric Analyzing and Sorting Core of the First Core Laboratory, National Taiwan University College of Medicine for providing the service

[15] Other environmental and occupation exposures such as exposure to metal dust, wood dust, coal dust, silica, stone dust, biologic dusts coming from hay dust or mold spores or other agricultural products, and occupations related to farming/livestock have also been shown to increase the risk for IPF

CDC42 is also known to be involved in cancer development and metastasis by the fasciculation of F-actin in the filamentous pseudopodia of the cells [88]

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Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis