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Cell life versus cell longevity: the mysteries surrounding the NAD+ precursor nicotinamide

However, cisplatin treatment is associated with toxic side effects and tumour cells can develop resistance to its effects thereby limiting its efficacy (Florea and Bsselberg 2011)

Kikuchi, N

doi: 10.1021/acs.jafc.8b04665 18 ZhaoXDZhangBWFuLJLiQLLinYYuXQ

The compound's selectivity extends to its membrane permeability characteristics, which allow efficient cellular uptake without affecting membrane integrity or cellular viability up to 100 M concentrations