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Health conditions linked to oxidative stress include Diabetes Cancer Alzheimers disease Parkinsons disease Male infertility Cardiovascular conditions like stroke, heart disease, atherosclerosis, and high blood pressure Inflammatory disorders like arthritis 2

J Clin Invest 124:7476

Growth Horm IGF Res., 2001

Similarly, in a screen of mutant KRAS lung adenocarcinoma cells, HG106 was found to specifically inhibit SLC7A11 function and decrease tumor burden in vivo via ROS induction and mitochondrial and endoplasmic reticulum dysfunction (78)