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Targeting lipid metabolism can reverse immunosuppression within the TME, thereby enhancing antitumor immune responses and ICI efficacy [181,182,183,184,185,186]

ERK1/2-mediated activation of DRP1 regulates mitochondrial dynamics and apoptosis in chondrocytes

Overall, triggering ferroptosis notably heightens the efficacy of temozolomide

This is not surprising, because the N-terminal residues (aa 67-137) are not solved in the crystal structure and the p(r) function showed an elongated tail, most probably the N-terminal region

Regular follow-up and monitoring of Vitamin B12 levels are essential to assess treatment effectiveness and ensure adequate management of the deficiency