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Transformation of a benign oral pigmentation to primary oral melanoma.Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics

Structural features Reticular prominent pigment network Globular numerous globules or blots Homogeneous brown pigmentation Combinations of the above Unclassified Distribution of pigment Central hypo/hyperpigmentation Eccentric peripheral hypo/hyperpigmentation* (uneven hypo/hyperpigmentation that reaches the border of the lesion) Multifocal hypo/hyperpigmentation (patchy appearance) *Note: eccentric peripheral hypo/hyperpigmentation can be seen in both atypical naevi and melanoma

Doctors diagnose these atypical moles based on at least 3 features: a size larger than 5 mm, unclear boundaries, irregular edges, and differing colours within the mole

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Further research is need to confirm this (4)