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The synergy claim is mechanistic, derived from the three peptides acting on different nodes of overlapping pathways (VEGF, NF-kB, ECM remodeling)

BPC-157 emerged from Croatian gastroenterology research into cytoprotection the idea that gastric juice contains substances that protect and heal the stomach lining

It is a recognized cosmetic ingredient (copper tripeptide-1) used in regulated skincare products worldwide

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